The Difference Between COPD and Emphysema Kelsey Seybold Clinic E cigarette use tied to increased COPD, asthma risk MDedge Smoking, Vaping and Increased Risk of COPD Elevated risk of developing COPD with e cigarette use: Study Emphysema and chronic bronchitis are both forms of COPD but affect different parts of the lungs. Emphysema damages the air sacs (alveoli), causing shortness of breath, while bronchitis inflames and narrows the Vaping and Lung Damage: What Pulmonologists Want You to Know