DermDx: Brown Macule on Lip Dermatology Advisor This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding Orale melanosis A collection of resources for RACGP exams Next Gen GP Text Book live webinars AKT and KFP questions Labial melanotic macule (brown spot on lip) (Stony Brook Case 1) dermatology dermatopathology This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips.