EVALUATION OF HEPATIC TOXICITY OF SEVEN DAY REPEATED DOSE GLUTATHIONE DEPLETING REGIMENS IN RATS Frontiers Role of Glutathione Depletion and Reactive Oxygen Species Generation on Caspase 3 Activation: A Study With the Kinase Inhibitor Staurosporine Highly Selective and Prolonged Depletion of Mitochondrial Glutathione in Astrocytes Markedly Increases Sensitivity to Peroxynitrite Journal of Neuroscience There are many studies showing low Glutathione levels with Parkinson's and Alzheimer's disease. Also several studies show low glutathione is considered to be one of the early biochemical changes in both Parkinson's Hepatic transcriptome and proteome responses against diethyl maleate induced glutathione depletion in the rat Archives of Toxicology Springer Nature Link Interleukin 4 deficiency protects mice from acetaminophen induced liver injury and inflammation by prevention of glutathione depletion Inflammation Research Springer Nature Link