There are zero randomized clinical trials on BPC 157. Zero. Here's what we actually know: it was isolated from stomach acid because researchers noticed those cells regenerate constantly in a harsh environment. Phosphodiesterase type 5 (PDE5) inhibitors are medications used to treat erectile dysfunction (ED) and pulmonary hypertension. They include sildenafil, vardenafil, tadalafil, and avanafil. These medications inhibit the PDE5 enzyme in endothelial cells, Peptide for erectile dysfunction: what actually works and what to watch for BPC 157 Erectile Dysfunction Study: What the Current Research Actually Shows BPC 157 erectile dysfunction study: what the current evidence actually shows Can BPC 157 Cause Erectile Dysfunction?