What Are B12 Injections? And Are They Safe? OmegaQuant Quick question why do people talk about B12 injections versus ingestible pills? I wish I injections. I do not have the cash for that little backstory. I've been eating vegan style for Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta analysis Irish Journal of Medical Science (1971 ) B12 Injections vs Pills Baltimore: Which Works? B12 SHOTS What are they for? Feeling tired, sluggish, or run down? A B12 injection may help support your body from the inside out Boosts energy levels Supports NAD+ vs. B12: What's the difference? NAD+ supports cellular energy, metabolism, and longevity at the mitochondrial level. B12 helps with red blood cell production, nerve health, and energyespecially if you're deficient.