Depression and Vaping Smokefree Teen Vaping and Anxiety: Why They're Connected Teens who vape or smoke more likely to experience depression and anxiety, study of over 60,000 u.s. students finds. Youth using both e cigarettes and traditional tobacco report the highest levels of mental Vaping and the Brain: Effects of Electronic Cigarettes and E Liquid Substances The Journal of Neuropsychiatry and Clinical Neurosciences Nicotine use and stress Study finds 'strong link' between vaping and depression