Vape vs Cigarette Nicotine: How Many 5% Vape Puffs Equal One Cig? How Many Puffs of Vape are Equal to a Cigarette? EDGE Vaping The nicotine content of many disposable vapes is equivalent to a pack of 20 cigarettes. If you don't smoke, don't vape. #NoSmokingMonth Public Health Agency How much nicotine is in a cigarette compared to a vape? Vaping The Guardian How Many Puffs of Vape is Equal to a Cigarette? UPENDS E cigarettes and Vaping Commercial Tobacco Use MN Dept. of Health